At the age of 22, Nai Lert started an imported goods business called Nai Lert Store and developed the first Ice Factory in the country. The factory’s site is located in the area of Sukhumvit Rd between Soi 5 & 7 (both Sois were named Soi Nai Lert).
Though Nai Lert kept his headquarters near the original shop, he expanded to other businesses in other parts of the city. He developed the Hotel de la Paix thereby creating the first hotel property of the family business. Nai Lert also expanded his business into transportation business; he introduced the first bus services in Thailand in 1913 to serve Bangkok commuters and later expanded the business into the first taxi service using imported cars, the White Boat Company operating pleasure boats, seagoing vessels and a public transportation service along the Klong Saen Saep from Pratunam. He also launched an even more innovative venture, the White Bus Company, with its first route running between Pratunam and Yotse Bridge, followed later by several other routes, including one to Silom Road. An innovation for commuters from the countryside was that passengers travelling by ferry could use the same ticket when transferring to the bus at Pratunam.